Package: REMixed 1.1.2

REMixed: Regularized Estimation in Mixed Effects Model

Implementation of an algorithm in two steps to estimate parameters of a model whose latent dynamics are inferred through latent processes, jointly regularized. This package uses 'Monolix' software (<https://monolixsuite.slp-software.com/>), which provide robust statistical method for non-linear mixed effects modeling. 'Monolix' must have been installed prior to use.

Authors:Auriane Gabaut [aut, cre], Ariane Bercu [aut], Mélanie Prague [aut], Cécile Proust-Lima [aut]

REMixed_1.1.2.tar.gz
REMixed_1.1.2.zip(r-4.7)REMixed_1.1.2.zip(r-4.6)REMixed_1.1.2.zip(r-4.5)
REMixed_1.1.2.tgz(r-4.6-any)REMixed_1.1.2.tgz(r-4.5-any)
REMixed_1.1.2.tar.gz(r-4.7-any)REMixed_1.1.2.tar.gz(r-4.6-any)
REMixed_1.1.2.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
REMixed/json (API)

# Install 'REMixed' in R:

install.packages('REMixed', repos = c('https://aurianegbt.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/aurianegbt/remixed/issues

Datasets:

dynFUN_demo - Dynamic functions demo

On CRAN:

4.30 score 2 stars 10 scripts 184 downloads 20 exports 42 dependencies

Last updated from:2cde1e8aff. Checks:9 OK. Indexed: yes.

Target	Result	Time
linux-devel-x86_64	OK	130
source / vignettes	OK	169
linux-release-x86_64	OK	129
macos-release-arm64	OK	136
macos-oldrel-arm64	OK	138
windows-devel	OK	89
windows-release	OK	107
windows-oldrel	OK	89
wasm-release	OK	101

Exports:BICc computeFinalTest cv.remix eBIC extract getMLXdir gh.LL indParm initStrat model.clairon model.pasin model.pk plotCalibration plotConvergence plotIC plotInit plotSAEM readMLX remix retrieveBest

Dependencies:cli codetools cpp11 deSolve doSNOW dplyr farver fastGHQuad foreach generics ggplot2 glue gmp gridExtra gtable isoband iterators labeling lifecycle magrittr MASS pillar pkgconfig purrr R6 RColorBrewer Rcpp rlang Rmpfr Rsmlx S7 scales snow stringi stringr tibble tidyr tidyselect utf8 vctrs viridisLite withr

REMixed_vignette

Rendered fromdoc.Rnwusingutils::Sweave

Last update: 2025-09-19
Started: 2025-09-19

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
AIC for remix object	AIC.remix
BIC for remix object	BIC.remix
BICc	BICc
Compute final estimation	computeFinalTest
REMixed algorithm over a grid of lambda	cv.remix
Dynamic functions demo	dynFUN_demo
eBIC	eBIC
extract remix results from cvRemix object	extract
Get monolix demo project path	getMLXdir
Adaptive Gauss-Hermite approximation of log-likelihood derivatives	gh.LL
Generate individual parameters	indParm
Initialization strategy	initStrat
Model from Clairon and al.,2023	model.clairon
Model from Pasin and al.,2019	model.pasin
Generate trajectory of PK model	model.pk
Plot of cv.remix object	plot.cvRemix
Calibration plot	plotCalibration
Log-likelihood convergence	plotConvergence
IC plot	plotIC
Plot initialization	plotInit
Display the value of parameters at each iteration	plotSAEM
Extract Data for REMixed Algorithm from a Monolix Project	readMLX
REMixed algorithm	remix
REMixed results	retrieveBest